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Environmental effects can be reduced by exploring alternatives and enhancing possibilities throughout the life cycle

Astrocytes, which preferentially accumulate Mn due to the presence of high-affinity Mn transporters (Sidoryk-Wegrzynowicz and Aschner, 2013), are primarily responsible for the glutamate uptake via GLAST and GLT (Rothstein et al., 1996

The Bottom Line Saxenda and Ozempic are both GLP-1 receptor agonists, but semaglutide (Ozempic/Wegovy) has become the clear preferred option for most patients

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Carefully manage the use of diuretics and RAAS blockers (e.g., ACE inhibitors, ARBs)