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doi: 10.1002/ptr.6959

GLP-1 analogues, such as semaglutide, are prescribed for people with type 2 diabetes, including those with the condition who have obesity, in order to promote weight loss and improve control of blood sugars

The relevance of this observation extends to the wider family of GPCRs, with individual effects almost certainly receptor-specific, as both -arrestin-biased 54 and G protein-biased 55 ligands have proved effective for individual receptors in preclinical studies

Some studies have suggested that L-carnitine may benefit heart health and exercise performance