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The intranasal GHK-Cu treatment was found to delay cognitive impairment, reduce amyloid plaques, and lower inflammation levels in the frontal cortex and hippocampus .37 Randomized controlled trials in human patients are needed to confirm the benefit of GHK-Cu for cognitive decline and Alzheimers disease as well as to evaluate safe and effective human dosing (the human dose equivalent of 15mg/kg in mice would be ~1.2mg/kg, though data on this or any other dosing nasally in humans is not currently available), but preliminary animal trials are promising

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Peer-reviewed studies demonstrate that GHK-Cu can: Stimulate fibroblast proliferation and collagen synthesis Increase glycosaminoglycan production Support wound contraction and remodeling Reduce oxidative stress and inflammation A major review published in the International Journal of Molecular Sciences describes GHK-Cu as a compound that resets gene expression to a healthier state, influencing over 4,000 human genes involved in tissue repair and anti-inflammatory processes