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Davinelli, F

GHK-Cu and Wound Healing Research Multiple animal studies have established the wound healing activity of GHK-Cu, with research in rabbit experimental wounds showing improved wound contraction, granular tissue formation, increased glutathione and ascorbic acid levels, and elevated collagen synthesis and fibroblast activation

3,4,5 These symptoms are likely due to the effects of increased production of neurotransmitters dopamine, norepinephrine, acetylcholine, and serotonin, 4,6 which act on the locus coeruleus, ventral tegmental area, and nucleus accumbens

Exposure to pro-oxidant stimuli usually induces Nrf2 activation and upregulation of antioxidant enzyme expression through binding to the antioxidant response element (ARE), localized in the antioxidant enzyme gene promoters

Other Causes of Nipple Soreness While latch issues are the most common cause of nipple pain, other conditions are common and can also contribute to soreness while breastfeeding