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[9] For wound healing specifically, the evidence is stronger than for cosmetic anti-aging, because wound models involve measurable endpoints (wound closure rate, tissue tensile strength, histological analysis) in controlled animal studies

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Simultaneous inhibition of aryl hydrocarbon receptor (AhR) and src abolishes androgen receptor signaling

M.ParlakgulG.GuneyE.InouyeK.HotamisligilG

This configuration supports receptor-level interaction within adipocytes while minimizing affinity for the growth hormone receptor, distinguishing it from full-length GH and preventing downstream IGF-1 pathway activation