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Additionally, sustained release of pro-inflammatory mediators has been shown to exert detrimental effects directly on hippocampal neurogenesis

ESI, electrospray ionization

In brief, the synovial tissues were collected, washed with PBS, chopped with scissors, and soaked in PBS mix with type I collagenase (4 mg/mL) in cell culture incubators for 3 h

While in animals it mediates neurotransmission, neuromodulation, and synaptic plasticity, in plants it regulates seed germination, root development, stomatal closure, and floral transition (Forrester et al