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By enhancing the efficiency of these enzymes, GPS facilitates the faster breakdown of alcohol and acetaldehyde, thereby mitigating their detrimental impact on liver health

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For in vivo experiments, the closest model would be the C57BL/6 mouse strain though degree of liver injury can vary between sub-strains without change in mechanism

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Ketone production increases mainly when the supply of glucose/acetoacetate decreases to maintain energy production