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(PubMed) Pearce EN, Leung AM, Blount BC, et al

MancinaRMDongiovanniPPettaSPingitorePMeroniMRamettaRet al

These studies demonstrate a novel pathway through which the status of GSH can enhance the levels of 25(OH)VD and that the use of combined VD+LC supplementation significantly lowers inflammation and increases the levels of GSH, vitamin D regulatory genes, and VDR, all of which are required to raise the blood levels of 25(OH)VD and reduce the inflammation levels

Only about 3.8% of users in clinical trials reported any side effects

Informed by the structural data of Pt GSTF8, the accompanying mutagenesis experiments and the QM/MM studies, we investigated the impact of a disulfide bond between C13 and GSH on dehydratase activity