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Therefore, we performed a meta-analysis of double-blind randomized placebo-controlled clinical trials to investigate the cardiovascular complications of GLP-1 receptor agonists in T2DM patients

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Assuming everyone took it, made no lifestyle changes and gained back more than half of the weight after discontinuation with no use as a maintenance drug afterwards, utilizing a very pessimistic penetration rate of 15%, even then it would be enough to have the obesity rate correct lower by more than 6%

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Mounjaro and Zepbound use this approach