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In some patients, AF is linked to excessive vagal activity, typically occurring at night and in the presence of a smaller left atrial (LA) volume

Oral and noninvasive alternatives are widely viewed as one of the next major commercial opportunities within obesity and diabetes therapeutics

These effects are likely mediated in part by improvements in glucose control and weight loss

On trial weight loss, retatrutide has produced higher figures (up to about 28% versus up to about 21% for tirzepatide), thanks to its third hormone target