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As a result, a vitamin B-12 deficiency can have serious implications for diabetics, including fatigue and depression, as well as other neurological effects

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According to the results of a national survey conducted in 2015, the annual rate of suicide attempts is three to five times greater in young adults aged 1825 years, compared with older age groups in the United States [Reference Piscopo, Cooney and Glasheen37]

[Bioorganic and Medicinal Chemistry Letters, 2000, vol