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Introduction In 2003, erastin, a novel compound was identified, which showed a selective lethality against human foreskin cells (BJeLR cells) expressing engineered mutated RAS oncogene while using high-throughput screening to find out 23,550 compounds for their ability to eliminate engineered tumorigenic cells (Dolma et al., 2003)

(PubMed) United Nations Children's Fund

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Additional ingredients like caffeine and rosemary extract provide complementary benefits through different mechanisms