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Terrill SJ, Jackson CM, Greene HE, Lilly N, Maske CB, Vallejo S, et al

The colour change upon mixing is due to GHK binding with Copper Ions to produce 1% of GHK Cu whilst 1% of GHK is left in free-form

Metformin's insulin-sensitising effects complement the insulin-secreting properties of GLP-1 receptor agonists , whilst the appetite suppression and gastric effects of the injections enhance the modest weight benefits of metformin

Given the overlap between expected medication side effects and the patients worsening gastrointestinal symptoms, the case presented a significant diagnostic challenge