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GLP-1s are generally safe, but some drugs have been withdrawn from the market due to long-term risks

The exact ingredients can vary between brands, but GLP-1 patches typically contain a combination of natural extracts and vitamins , like: berberine (the main active ingredient, thought to support GLP-1 release) green tea extract cinnamon extract mint pomegranate extract a selection of vitamins None of these are clinically approved for weight loss , and the amounts absorbed through the skin are not well studied or proven to be effective

This poses another limitation, casting doubt on the generalizability of our findings

Before it leads to harm to the body, weight loss becomes a crucial priority

It includes GLP-1 receptor activity, but unlike semaglutide, it is a triple agonist, also targeting GIP and glucagon receptors for broader metabolic effects