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MOTS-C MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a naturally occurring peptide encoded within mitochondrial DNA, playing a key role in cellular metabolism and energy regulation

The ability to switch from glucagon to GLP-1 in times of metabolic stress may be a critical way the body maintains blood sugar control.

It's a functional marker it tells you the gut lining is not just intact but actually working

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