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For both dipeptides, subsequent exchange with full-length peptides restored the expected receptor specificities, confirming that the dipeptide intermediate was replaced

LL-37, an antimicrobial peptide, also carries anti-inflammatory properties useful in conditions where infection and inflammation overlap

Mechanisms include increased aromatisation of testosterone to oestradiol, functional hypogonadotropic hypogonadism, inflammation, oxidative stress and impaired testicular thermoregulation

Liu X, Wang W, Song G, Wei X, Zeng Y, Han P, Wang D, Shao M, Wu J, Sun H, et al

The cell has several protective mechanisms that minimize the toxic potential of these compounds