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These alterations have been most consistently observed in white matter tracts within the fronto-limbic network and may underlie impaired emotion regulation and cognitive dysfunction commonly reported in TRD patients 105,106,107 and in WKY rats 13,14,16

10.1016/j.exger.2017.09.016 153 KimD.HughesT

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The levels of GBB and L-CN in human plasma and urine were similar to those in rats, suggesting that humans and rats have similar GBB and L-CN expression levels

Gliadin has been observed to damage the intestinal barrier and then stimulate inflammatory immune responses