Alternating Dihexa with other cognitive research compounds acting through different mechanisms can be an effective protocol design strategy that reduces tolerance risk while maintaining neuroplastic stimulus
SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress
This was associated with reduced pro-inflammatory gene expression (e.g., Il2, Ifng ) (185)
Noam Sobel (00:03:46) Sponsors: ROKA, Thesis, Helix Sleep (00:06:46) Olfaction Circuits (Smell) (00:14:49) Loss & Regeneration of Smell, Illness (00:21:39) Brain Processing of Smell (00:24:40) Smell & Memories (00:27:52) Sponsor: AG1 (Athletic Greens) (00:29:07) Humans & Odor Tracking (00:39:25) The Alternating Nasal Cycle & Autonomic Nervous System (00:48:18) Cognitive Processing & Breathing (00:54:47) Neurodegenerative Diseases & Olfaction (01:00:12) Congenital Anosmia (01:05:01) Sponsor: InsideTracker (01:06:19) Handshaking, Sharing Chemicals & Social Sensing (01:15:07) Smelling Ourselves & Smelling Others (01:22:02) Odors & Romantic Attraction (01:24:58) Vomeronasal Organ, Bruce Effect & Miscarriage (01:40:20) Social Chemo-Signals, Fear (01:50:26) Chemo-Signaling, Aggression & Offspring (02:03:57) Menstrual Cycle Synchronization (02:12:11) Sweat, Tears, Emotions & Testosterone (02:27:46) Science Politics (02:37:54) Food Odors & Nutritional Value (02:45:34) Human Perception & Odorant Similarity (02:52:12) Digitizing Smell, COVID-19 & Smell (03:05:50) Medical Diagnostic Future & Olfaction Digitization (03:10:55) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer Day 128 How Psilocybin Can Rewire Our Brain, Its Therapeutic Benefits & Its Risks In this episode, I discuss what psilocybin is (chemically) and how it works at the cellular and neural circuit level to trigger neuroplasticity, which is our brains ability to rewire itself in ways that lead to long-lasting shifts in our emotional, cognitive and behavioral patterns and abilities
These signaling processes are often studied in relation to extracellular matrix dynamics , connective signaling balance, and adaptive communication behavior across dermal and epithelial environments
