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The Relationship of Menopausal Hormone Therapy and Other Factors to the Risk of Diabetic Retinopathy in the Wisconsin Epidemiologic Study of Diabetic Retinopathy

However, the development and clinical application of these therapies will continue to face numerous challenges that must be addressed to optimize their efficacy and safety [125,126]

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The peroxynitrite radical, which damages cells, is created when too much NO combines with a superoxide anion to oxidise and nitrate macromolecules, including GSH, proteins, lipids, and DNA