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The inflammaging process involving the accumulation of pro-inflammatory senescent cells triggers immunosuppressive mechanisms to maintain tissue homeostasis [122]

Bitter orange (synephrine) This citrus extract contains synephrine, a stimulant commonly used in weight loss products

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While these compounds differ in their molecular structure, they share common mechanisms of action in combating oxidative stress, which are particularly relevant to ED where oxidative stress significantly impairs endothelial cell function and NO signaling [8]

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