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While capsules and other forms may offer convenience, they cannot guarantee the same efficacy and reliability critical for scientific inquiry

doi: 10.1126/science.aal1585 133 HuangNWangPJiangD

As biofilm matures without disruption, its microbial character shifts: beneficial species decline and potentially harmful bacteria gain dominance, making the restoration of balance progressively more difficult

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New or worsening nephropathy, defined as persistent macroalbuminuria, persistent doubling of the serum creatinine level, and a creatinine clearance of 30 ml/min/1.73 m 2 should receive metformin and SGLT2i (Fig