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Cartilage and Musculoskeletal Biology Research As noted in the mechanism section, published research has begun to examine this compounds interactions with cartilage biology and chondrocyte function

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Once activated, SIRT1 enhances mitochondrial function by deacetylating and activating PGC-1 , which collaborates with AMPK to drive mitochondrial oxidative metabolism (114)

Cells were transfected with corresponding expression constructs for 24 h before 4% formaldehyde fixation