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To denature the proteins, 120 L of 8 M urea in 50 mM Tris-HCl (pH 8) was added

Think of the C rating like a speed limit for energy flow

Although initial studies suggested that GSH depletion was only a byproduct of oxidative stress generated during cell death, recent discoveries suggest that GSH depletion and post-translational modifications of proteins through glutathionylation are critical regulators of apoptosis

Spokespeople for Oz and Kennedy did not respond to requests for comment about how they would handle the policy decision